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Image Search Results
Journal:
Article Title: A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis
doi: 10.1172/JCI200318038
Figure Lengend Snippet: Time course of glomerular Vn (a) and endogenous PAI-1 (b) staining in OX-7–induced nephritis. Data are from three rats at each timepoint. NC, normal control.
Article Snippet:
Techniques: Staining
Journal:
Article Title: A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis
doi: 10.1172/JCI200318038
Figure Lengend Snippet: Colocalization of PAI-1R with Vn. A glomerulus from a d1 animal sacrificed 1 hour after PAI-1R injection. Staining for (a) rat Vn (red) and (b) PAI-1R (green). (c) Double staining for Vn and PAI-1R. Injected PAI-1R colocalized with endogenous rat Vn in the mesangium. Normal control (d) and disease control (e) rats showed Vn staining only in glomerulus, and no staining for human PAI-1 in kidney.
Article Snippet:
Techniques: Injection, Staining, Double Staining
Journal:
Article Title: A mutant, noninhibitory plasminogen activator inhibitor type 1 decreases matrix accumulation in experimental glomerulonephritis
doi: 10.1172/JCI200318038
Figure Lengend Snippet: Relative glomerular mRNA expression of TGF-β1, PAI-1, fibronectin, and type I collagen. Glomerular mRNA levels of fibronectin and type I collagen were significantly reduced at d6, but the overexpression of TGF-β1 and PAI-1 was not changed in the PAI-1R–treated group. *P < 0.001 vs. normal control; #P < 0.02 vs. disease control; ‡P < 0.01 vs. disease control.
Article Snippet:
Techniques: Expressing, Over Expression